Models#

list_models

List all available models.

Vision Models#

UNI

🤗Hugging Face GitHub Paper [Chen et al., 2024] General-purpose self-supervised model for pathology

UNI2

🤗Hugging Face GitHub Paper [Chen et al., 2024] An improved version of UNI

GigaPath

🤗Hugging Face GitHub Paper [Xu et al., 2024] A whole-slide foundation model for digital pathology

PLIPVision

🤗Hugging Face GitHub Paper [Huang et al., 2023] Pathology Language-Image Pretraining (PLIP)

CONCHVision

🤗Hugging Face GitHub Paper [Lu et al., 2024] CONtrastive learning from Captions for Histopathology (CONCH)

Virchow

🤗Hugging Face Paper [Vorontsov et al., 2024] A foundation model for clinical-grade computational pathology and rare cancers detection

Virchow2

🤗Hugging Face Paper [Zimmermann et al., 2024] Scaling self-supervised mixed magnification models in pathology

Phikon

🤗Hugging Face GitHub Paper [Filiot et al., 2023] Scaling self-Supervised Learning for histopathology with Masked Image Modeling

PhikonV2

🤗Hugging Face GitHub Paper [Filiot et al., 2024] A large and public feature extractor for biomarker prediction

HOptimus0

🤗Hugging Face GitHub [Saillard et al., 2024] Vision foundation model

HOptimus1

🤗Hugging Face GitHub [Bioptimus, 2025] Vision foundation model

H0Mini

🤗Hugging Face GitHub Paper [Filiot et al., 2025] A distilled version of H-optimus-0

HibouB

🤗Hugging Face GitHub Paper [Nechaev et al., 2024] A family of foundational vision transformers for pathology

HibouL

🤗Hugging Face GitHub Paper [Nechaev et al., 2024] A family of foundational vision transformers for pathology

Multimodal Models#

PLIP

🤗Hugging Face GitHub Paper [Huang et al., 2023] Pathology Language-Image Pretraining (PLIP)

CONCH

🤗Hugging Face GitHub Paper [Lu et al., 2024] CONtrastive learning from Captions for Histopathology (CONCH)

Titan

🤗Hugging Face GitHub Paper [Ding et al., 2024] Multimodal whole slide foundation model for pathology

Prism

🤗Hugging Face Paper [Shaikovski et al., 2024] A multi-modal generative foundation model for slide-level histopathology, the Prism models encode slide-level embeddings from Virchow.

OmiCLIP

🤗Hugging Face GitHub Paper [Chen et al., 2025] A visual-omics foundation model to bridge histopathology with spatial transcriptomics

Segmentation Models#

Instanseg

GitHub Paper [Goldsborough et al., 2024] An embedding-based instance segmentation algorithm optimized for accurate, efficient and portable cell segmentation.

NuLite

GitHub Paper [Tommasino et al., 2024] Nuclei instance segmentation and classification

GrandQCTissue

GitHub Paper [Weng et al., 2024] Tissue segmentation model from GrandQC

GrandQCArtifact

GitHub Paper [Weng et al., 2024] Artifact segmentation model from GrandQC

PathProfilerTissueSegmentation

GitHub Paper [Haghighat et al., 2022] Tissue segmentation model from PathProfiler

SMPBase

This is a base class for any models from segmentation models pytorch

Tile Prediction Models#

SpiderBreast

🤗Hugging Face Tile prediction model on different organs

SpiderColorectal

🤗Hugging Face Tile prediction model on different organs

SpiderSkin

🤗Hugging Face Tile prediction model on different organs

SpiderThorax

🤗Hugging Face Tile prediction model on different organs

Tile Prediction Models (Computer vision features)#

These models are based on OpenCV but provided with a model inferface.

Brightness

Calculate the brightness of a tile.

Canny

Calculate the canny edge detection score of a tile.

Contrast

Calculate the contrast of a tile.

Entropy

Calculate the entropy of a tile.

HaralickTexture

Calculate texture features using Gray Level Co-occurrence Matrix (GLCM).

Saturation

Calculate the color saturation of a tile.

Sharpness

Calculate the sharpness of a tile.

Sobel

Calculate the sobel of a tile.

SplitRGB

Calculate the RGB value of a tile.

Base Models#